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  • دکتری (1377)

    فیزیک پزشکی

    دانشگاه تربیت مدرس،

  • کارشناسی‌ارشد (1370)

    فیزیک پزشکی

    دانشگاه تربیت مدرس،

  • تعیین مشخصات فیزیکی- مكانیكی بافت های سالم و بیمار با پردازش تصاویر فراصوتی
  • درمان هدفمند با تابش امواج فراصوت (لیزر) در حضور نانوحامل های محتوی دارو
  • آزمایشگاه فراصوت و لیزر

داده ای یافت نشد

Stress distribution analysis in healthy and stenosed carotid artery models reconstructed from in vivo ultrasonography

Effat Soleimani, Manijhe Mokhtari-Dizaji, Nasser Fatouraee, Hazhir Saberi
Journal PapersUltrasonography , 2021 January 5, {Pages }

Abstract

Purpose:This study was to evaluate the accuracy of the reconstructed models from ultrasound image processing by comparing the radial displacement waveforms of the subject-specific artery model and to find the stress changes in the proximal shoulder, throat, and distal shoulder of the plaques depending on the degree of carotid artery stenosis.Methods:Three groups of subjects including healthy, less, and more than 50% carotid stenosis were evaluated with ultrasonography. 2D transverse imaging of the common carotid artery was carried to reconstruct geometry. A longitudinal view of the same region was recorded to extract the Kelvin viscoelastic model parameters. Pulse pressure waveform and the effective pressure of perivascular tissue was loade

Correlation between the Energy Density of Ultraviolet Radiation and Skin Thickening In an Animal Mouse Model: Induction of Trichoepithelioma in a Mouse Model

Mohadeshe Estaji, Manijhe Mokhtari-Dizaji, Mansoureh Movahedin, Sahar Ghaffari Khaligh
Journal PapersIranian Journal of Medical Physics , Volume 18 , Issue 2, 2021 March , {Pages 106-110 }

Abstract

Ultraviolet (UV) radiation causes direct and indirect damage to the cell structure, thereby increasing the aging process. Ultraviolet B-rays (UVB)(with 280-320 nm wavelengths) cause direct damage to the skin, and the portion that reaches the epidermal cells induces biological damage [1] and the most important biological damage is inflicted by DNA damage. With UVB absorption, thymine bases in the DNA bind to adjacent thymine [2]. This evidence can affect protein synthesis. The accumulation of unrepaired damages can disrupt the cell cycle and create cell death. Moreover, these damages can sometimes destroy the cell apoptotic ability and increase the malignancies. The results depend on the type of tissue, UV dose, and its wavelength [3]. UV ra

Non-invasive estimation of cardiac wall stress by using tissue doppler-echocardiography ultrasound images: People with coronary artery stenosis

MJ Khosravanipour, M Mokhtari-Dizaji, F Farhan, R Sattarzadeh-Badkoubeh
Journal PapersJournal of Acoustical Engineering Society of Iran , Volume 8 , Issue 2, 2021 March 10, {Pages 27-35 }

Abstract

In this study, a method for non-invasive estimation of stress on the heart wall in the diastole phase is presented using ultrasound echocardiography and tissue Doppler imaging. The aim of this study was to evaluate the stress on the heart wall as a pre-diagnosis to identify people with coronary artery stenosis. 29 patients with stenosis of more than 70%, 30 patients with stenosis of 50 to 70% and 35 healthy human participated in this study as a control group. the average stress of anterior and intraventicular septum was estimated non-invasively by considering wall thickness, left ventricular dimensions, and end-diastolic pressure by Using 2D echocardiography, tissue Doppler and Doppler ultrasound imaging techniques. The statistical analysis

COMPARISON OF TWO THICK SHELL MODELS PERFORMANCE IN NONINVASIVE EVALUATION OF MYOCARDIAL WALL STRESS

MJ KHOSRAVANIPOUR, M MOKHTARI-DIZAJI, F FARHAN, ...
Journal Papers , , {Pages }

Abstract

Low-intensity ultrasound as a novel strategy to improve the cytotoxic effect of oncolytic reovirus on colorectal cancer model cells

N Sharifi, H Soleimanjahi, M Mokhtari-Dizaji, RS Banijamali, ...
Journal Papers , , {Pages }

Abstract

Determination of optimal parameters of ultrasonic waves on permatogenesis process of neonate mouse testis

S Mohamadi, M Movahedin, M Mokhtari Dizaji
Journal Papers , , {Pages }

Abstract

Effect of cross-sectional area of high-intensity focused ultrasound (HIFU) on the thermal distribution of the target tissue

M Mokhtari-dizaji, S Mortazavi
Journal Papers , , {Pages }

Abstract

Assessing the short-term effects of radiotherapy on the shear modulus of the common carotid artery as a new biomarker of radiation-induced atherosclerosis.

A Mohammadkarim, M Mokhtari-Dizaji, A Kazemian, H Saberi, NA Yazdi, ...
Journal Papers , , {Pages }

Abstract

Correlation between the Energy Density of Ultraviolet Radiation and Skin Thickening In an Animal Mouse Model: Induction of Trichoepithelioma in a Mouse Model

M Estaji, M Mokhtari-Dizaji, M Movahedin, S Ghaffari Khaligh
Journal Papers , , {Pages }

Abstract

Assessment of left ventricular torsion in long axis view in patients with chronic stenosis of coronary arteries

Ali Jabari, Manijeh Mokhtari-Dizaji, Zahra Arab-Bafrani, Elham Mosavi, Leili Mahani, Mohammad Mostakhdem Hashemi
Journal PapersCaspian Journal of Internal Medicine , Volume 11 , Issue 1, 2020 January , {Pages 21 }

Abstract

Background:Left ventricular torsion is one of the most important biomechanical parameters of heart that routinely is measured in short axis view. A review of the literature has indicated that assessment of left ventricular torsion in short axis view has some limitations. In the present study, we evaluated whether torsion angle assessment in long axis view can be used as a diagnostic biomechanical marker in patients with coronary artery disease (CAD).Methods:We assessed 20 males and 15 females who suffered from CAD and 24 healthy males and females. Two dimensional echocardiography images were scanned in cine loop format position throughout four cardiac cycles at basal and apical levels in the long axis view (4CH). Peak torsion angle in long

The effect of ultrasound hyperthermia with gold nanoparticles on retinoblastoma Y79 cells

Somayeh Moradi, Manijeh Mokhtari-Dizaji, Fariba Ghassemi, Shahab Sheibani, Fahimeh Asadi Amoli
Journal Papersbio-systems , Volume 4 , Issue 8, 2020 May 9, {Pages 9 }

Abstract

The purpose of this study was to evaluate the possible synergistic effect of gold nano-therapy (Au-NPs) on Y79 cells treated with ultrasonic hyperthermia. The cells in the presence and absence of gold nanoparticles were subjected to ultrasonic irradiation (3 MHz, 1 W/cm2, 40% pulse mode). Gold nanoparticles with an average diameter of 60 nm were synthesized. The cell viability of the Y79 cells was evaluated 48 h after performing 0.5–11 min hyperthermia with and without Au-NPs using the MTT assay. There was no cytotoxicity with 1.7 μg/mL Au-NP concentration. Moreover, the results revealed a significant difference in the cell viability between the control group and the groups with a hyperthermia period of more than 4 min. The results indic

Correlation of energy density of ultraviolet radiation with skin thickening in an animal mouse model: Creation of a Trichoepithelioma model

Manijhe Mokhtari-Dizaji, Mohadeshe Estaji, Mansoreh Movahedin, Sahar Ghaffari Khaligh
Journal PapersIranian Journal of Medical Physics , 2020 March 16, {Pages }

Abstract

Introduction: Ultraviolet (UV) radiation to the skin causes oxidative damage and causes cancer in the epidermis. There seems to be a relationship between the thickening of the skin layer and the carcinogenicity. The aim of this study was to establish a rare benign skin lesion of Trichoepithelioma in an animal model and to investigate the relationship between the radiation dose of ultraviolet waves with thickening of the skin layer resulting from high-frequency ultrasound images.Materials and Methods: To investigate the skin damage process, 25 C57BL6 mice were irradiated with UVB (5 times a week for 9 weeks) with an energy density of 135, 270, 405, 540, 675, 810, 945, 1080 and 1215 J/m2, from the first week to the ninth week, respectively. T

Effect of fullerene nanoemulsion on the repair of wrinkles induced by UVB radiation: A c57bl6 mice model

Mohadese Estaji, Manijhe Mokhtari‐Dizaji, Mansoureh Movahedin, Arash Padash, Sahar Ghaffari Khaligh
Journal PapersSkin Research and Technology , 2020 July 4, {Pages }

Abstract

Introduction The effect of fullerene nanoemulsion on skin wrinkle repair in an animal model was evaluated using ultrasonic images processing. Methods Wrinkles were created in C57BL6 mice during 35?days of UVB radiation. Then, to investigate the therapeutic effect of fullerene nanoemulsions, mice were divided into three groups of control, UVB radiation, and treatment with fullerene nanoemulsion. Stable fullerene nanoemulsions were prepared using shear equalization. The therapeutic effect of fullerene nanoemulsion was investigated by extracting the skin thickness and mechanical parameters. Histology studies were performed to confirm the reliability of the treatment. Results A significant decrease was observed in the thickness of the epi

Increasing the efficiency of the retinoblastoma brachytherapy protocol with ultrasonic hyperthermia and gold nanoparticles: A rabbit model

Somayeh Moradi, Manijeh Mokhtari-Dizaji, Fariba Ghassemi, Shahab Sheibani, Fahimeh Asadi Amoli
Journal PapersInternational Journal of Radiation Biology , 2020 October 16, {Pages Jan-34 }

Abstract

Purpose This study purposed to evaluate the efficacy of brachytherapy with the modality of ultrasonic hyperthermia in the presence of gold nanoparticles (GNPs) on an ocular retinoblastoma tumor in an animal model of the rabbit. Materials and Methods Gold nanoparticles (GNPs) were synthesized and confirmed by UV-vis spectroscopy, scanning electron microscopy and dynamic light scattering. Rabbit eyes were exposed to an ultrasonic continuous mode to reach 42 ?C, and then turned into a pulse mode (40%) to maintain in the hyperthermia range (42-45 ?C) for 30 min. For in vivo experiments, a retinoblastoma tumor was induced by the injection

Effect of 3 MHz ultrasound radiation on retinoblastoma cell line

S Moradi, M Mokhtari Dizaji, F Ghassemi, S Sheibani, F Asadi Amoli
Journal PapersJournal of Acoustical Engineering Society of Iran , Volume 8 , Issue 1, 2020 September 10, {Pages 06-Jan }

Abstract

Ultrasound hyperthermia is a new way to treat cancerous tumors. Retinoblastoma is one of the most common malignant ocular tumors in children. Since hyperthermia is an effective treatment for cancer cells, the effect of hyperthermia on retinoblastoma cells was investigated in this study. The purpose of this study was to determine the effect of duration of 3 MHz ultrasound hyperthermia on Y79 cell death after 48 hours using MTT assay. In this study, the percentage of cell viability after 48 hours in treatment groups with a duration of hyperthermia more than 4 minutes was significantly different from the control group and in the treatment group with hyperthermia time of 9 minutes and 11 minutes, 50% and 69% of cells were killed, respectively.

Effect of Acoustic Cavitation on Mouse Spermatogonial Stem Cells: Colonization and Viability

Zeinab Hormozi Moghaddam, Manijhe Mokhtari‐Dizaji, Mansoureh Movahedin
Journal PapersJournal of Ultrasound in Medicine , 2020 September 2, {Pages }

Abstract

Objectives The mechanical index has long been one of the main criteria used to assess the safety limits for therapeutic medical applications. However, the safety of the mechanical index parameter is considered to be unknown in male fertility, which has a very significant role in vitro conditions. In this study, the effect of cavitation interactions due to mechanical index regions was evaluated on spermatogonial stem cells. Methods The acoustic pressure and mechanical index equations at the low intensities and the intended frequency were modeled and solved. The mechanical index average of 40 kHz frequency was selected as subthreshold, 0.70, and above the cavitation threshold. Neonatal spermatogonial stem cells were cultured. Spermatogon

The effect of ultrasound hyperthermia with gold nanoparticles on retinoblastoma Y79 cells (vol 53, pg 111, 2020)

Somayeh Moradi, Manijhe Mokhtari-Dizaji, Fariba Ghassemi, Shahab Sheibani, Fahimeh Asadi Amoli
Journal PapersGOLD BULLETIN , Volume 53 , Issue 04-Mar, 2020 December 1, {Pages 167-167 }

Abstract

The publication of this article unfortunately contained a mistake.

A Novel Ultrasonic Gel Phantom Dosimetry for Evaluation of the Dose Response

Neda Goharpey, Manijhe Mokhtari-Dizaji, Mohsen Bakhshandeh
Journal PapersJournal of the Korean Physical Society , Volume 77 , Issue 12, 2020 December , {Pages 1238-1247 }

Abstract

Ultrasonic imaging is able to detect structural changes due to chemical reactions occurring due to ionizing irradiation. The purpose of this study to create a gel phantom dosimeter (developed MAGIC gel), which has ultrasonic properties equivalent to human tissue for readout with ultrasonic imaging. The speed of sound and the attenuation coefficient were determined as a function of the absorbed dose in the range of 0–50 Gy by using this dosimeter. A gel phantom was prepared by adding MAGIC polymer gel proprietary combinations in ultrasonic soft tissue-mimicking gel. Then, the ultrasonic parameters (response) of the samples, including the propagation speed of sound (SOS) and the attenuation coefficient (BUA) were measured in the absorbed d

Low-intensity ultrasound combined with allogenic adipose-derived mesenchymal stem cells (AdMSCs) in radiation-induced skin injury treatment

Zeinab Hormozi Moghaddam, Manijhe Mokhtari-Dizaji, Mohammad Ali Nilforoshzadeh, Mohsen Bakhshandeh, Sahar Ghaffari Khaligh
Journal PapersScientific Reports , Volume 10 , Issue 1, 2020 November 17, {Pages 19-Jan }

Abstract

Mesenchymal stem cells are mechano-sensitive cells with the potential to restore the function of damaged tissues. Low-intensity ultrasound has been increasingly considered as a bioactive therapeutic apparatus. Optimizing transplantation conditions is a critical aim for radiation-induced skin tissue injury. Therefore, the therapeutic function of adipose-derived mesenchymal stem cells to ultrasound stimulus was examined based on the mechanical index (MI). Mesenchymal stem cells were isolated from the adipose tissues of mature guinea pigs. An ultrasound system (US) was constructed with a 40 kHz frequency. The radiation-induced skin injury model was produced on the abdominal skin of guinea pigs by 60 Gy of radiation. Then, they were divided to

Echocardiographic Assessment of the Left Ventricular Physical Parameters: A Comparison Study in Patients With Significant and Non-Significant Coronary Artery Disease

Zeinab Alsadat Ahmadi, Manijhe Mokhtari-Dizaji, Anita Sadeghpour, Hamideh Khesali, Ata Firouzi
Journal Papers , 2020 November 12, {Pages }

Abstract

BackgroundIn this study, physical parameters of the strain of left ventricle (LV), wall stress with a thick-walled ellipsoidal model, and elastic modulus of LV were extracted for distinguishing patients who were stent candidates.

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دروس نیمسال جاری

  • دكتري
    امواج و ميدانهاي الكترومغناطيسي غير يونساز و كاربرد آن در پزشكي ( واحد)
    دانشکده علوم پزشکی، گروه فيزيك پزشكي
  • كارشناسي ارشد
    اصول فيزيكي دستگاههاي علوم آزمايشگاهي ( واحد)
  • كارشناسي ارشد
    اصول فيزيكي دستگاههاي علوم آزمايشگاهي ( واحد)
  • كارشناسي ارشد
    امواج فرا صوت و كاربرد آنها در پزشكي 1 ( واحد)
  • كارشناسي ارشد
    امواج فرا صوت و كاربرد آنها در پزشكي 1 ( واحد)

دروس نیمسال قبل

  • كارشناسي ارشد
    بيولوژي سلولي و ژنتيك ( واحد)
    دانشکده علوم پزشکی، گروه فيزيك پزشكي
  • كارشناسي ارشد
    ليزر و كاربرد آن در پزشكي ( واحد)
  • كارشناسي ارشد
    الكتريسيته، مغناطيس و كاربرد آنها در پزشكي ( واحد)
  • كارشناسي ارشد
    نور و فيزيك ديدگاني ( واحد)
  • كارشناسي ارشد
    نور و فيزيك ديدگاني ( واحد)
  • 1390
    مرادپور, سجاد
    بررسي تكرار تابش سونو -فوتوديناميك تراپي با حضور نانوپليمرهاي محتوي متيلن بلو در درمان تومور آدنوكار سينوماي پستان موشBalb/c
  • 1391
    تمدن يزديان, مرضيه
  • 1396
    فقيه, ولي اله
  • 1397
    ساماني پور, شيما
  • 1397
    طالبيان درزي, صديقه
  • 1398
    خدادادي, اسما
  • 1398
    صادقي گوغري, اميد
  • 1399
    عبدالحسين, هديل صباح
  • 1390
    اميري فلاح, زينب
    اثر ليزر كم توان فروسرخ نزديك بر تكثير پذيري سلول هاي بنيادي عصبي و عملكرد مسير بينايي بدنبال القاي موضعي دميليناسيون در كياسما و عصب بينايي موش صحرايي
  • 1396
    اميري, حسين
  • 1397
    اردوني, جلال
  • 1397
    شهيداني, اكرم
  • 1399
    شورچه, صادق
  • 1399
    عبدالله, سميره
  • مدیر گروه فیزیک پزشکی
  • سردبیر نشریه انجمن مهندسی صوتیات ایران
  • عضو هیات تحریریه نشریه انجمن مهندسی صوتیات ایران
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