En
  • دکتری (1394)

    ویروس شناسی

    علوم پزشکی تهران، تهران، ایران

  • کارشناسی‌ارشد (1388)

    ویروس شناسی

    علوم پزشکی تهران، تهران، ایران

  • کارشناسی (1385)

    علوم آزمایشگاهی

    علوم پزشکی مشهد، مشهد، ایران

  • ویروس های تنفسی: اپیدمیولوژی مولکولی، تشخیص و درمان
  • شناسایی و آنالیز پاتوژن های مختلف ویروسی در نمونه های بالینی
  • ویروسهای دخیل در سقط جنین و ناباروری

    سمیه شاطی زاده ملک شاهی كارشناسى ارشد خود را در رشته ویروس شناسی پزشكى از دانشگاه علوم پزشكى تهران دريافت كرد و در سال 1389 در مقطع دكترى در رشته ویروس شناسی پزشکی در دانشگاه علوم پزشكى تهران پذيرفته شد و در سال ١٣٩٤ از اين دانشگاه فارغ التحصيل شد. او از اسفند 1396 به عنوان استاديار ویروس شناسی در گروه ویروس شناسی دانشگاه تربيت مدرس مشغول به خدمت است.

    ارتباط

    رزومه

    Survey of BK and JC polyomaviruses, human cytomegalovirus and human papillomavirus in different types of brain tumors in Iranian patients

    Erfaneh Hosseini, Somayeh Shatizadeh Malekshahi, Masoumeh Pourjabali, Nazanin-Zahra Shafiei-Jandaghi, Nastaran Ghavvami, Jila Yavarian
    Journal PapersGene Reports , 2021 March 26, {Pages 101106 }

    Abstract

    ObjectiveViral infections account for 15–20% of human cancers worldwide.The potential roles of various viruses, such as polyomaviruses (PyV), human cytomegalovirus (HCMV) and human papillomavirus (HPV) in brain tumors remain unclear. The aim of this study was investigation of the prevalence of different viruses in different types of brain tumors including glioblastoma multiform (GBM), astrocytoma, oligodendroglioma, meningioma and B cell lymphoma. Meanwhile we described the relation of age/gender and cancer distribution.Methods86 formalin-fixed paraffin-embedded samples have examined for the prevalence of JCPyV, BKPyV, HCMV and HPV in different brain tumors. We tested JCPyV, BKPyV by using Real Time PCR targeting the large T-antigen and H

    Frequency of Cytomegalovirus Viral Load in Iranian Human Immunodeficiency Virus-1-Infected Patients with CD4+ Counts< 100 Cells/mm3

    Mohammad Reza Jabbari, Hoorieh Soleimanjahi, Somayeh Shatizadeh Malekshahi, Mohammad Gholami, Leila Sadeghi, Minoo Mohraz
    Journal PapersIntervirology , 2021 March 31, {Pages 05-Jan }

    Abstract

    Objectives: The aim of present work was to assess cytomegalovirus (CMV) viremia in Iranian human immunodeficiency virus (HIV)-1-infected patients with a CD4+ count< 100 cells/mm 3 and to explore whether CMV DNA loads correlate with CD4+ cell counts or associated retinitis. Methods: This study was conducted at the AIDS research center in Iran on HIV-1-infected patients with CD4+ count< 100 cells/mm 3, antiretroviral therapy-naive, aged≥ 18 years with no previous history of CMV end-organ disease (CMV-EOD). Results: Thirty-nine of 82 patients (47.56%) had detectable CMV viral load ranging from 66 to 485,500 IU/mL. CMV viral load in patients with retinitis ranges from 352 to 2,720 IU/mL, and it was undetectable in 2 patients. No significant a

    A review of influenza virus infection during pregnancy

    H Bagheri, S Shatizadeh Malekshahi, M Ravanshad
    Journal Papers , , {Pages }

    Abstract

    SARS-CoV-2: an imperative maternal-fetal concern

    Z Heydarifard, J Yavarian, SS Malekshahi, S Zadheidar, T Mokhtari-Azad, ...
    Journal Papers , , {Pages }

    Abstract

    Prevalence and clinical manifestations of herpes simplex virus infection among suspected patients of herpes simplex encephalitis in Shiraz, Iran

    A Babaei, SS Malekshahi, N Pirbonyeh, A Moattari
    Journal Papers , , {Pages }

    Abstract

    Prevalence of Human Metapneumovirus Infections in Iran: A Systematic Review and Meta-Analysis

    Somayeh Shatizadeh Malekshahi, Jila Yavarian, Nazanin-Zahra Shafiei-Jandaghi, Talat Mokhtari-Azad, Mohammad Farahmand
    Journal Papers , 2020 February 20, {Pages 11-Jan }

    Abstract

    Background: We sought to systematically review the literature and perform a meta-analysis by assessing the prevalence of human metapneumovirus (hMPV) infections from a number of studies conducted in Iran. Methods: Entire studies addressing epidemiology of hMPV in Iran using data from PubMed, Scopus, Science Direct, Web of science, Google Scholar, Embase, and national Persian databases up to June 2019 were included. Results: The estimated prevalence of hMPV was 8.9%(95% CI 5.4–14.2) in different regions in Iran. Compared to the global rate, in Iran hMPV infection presented an intermediate prevalence rate. The majority of hMPV positive patients were pediatric populations with pooled prevalence of 7.6%(I 2= 95%, 95% CI 3.5–15.6). Conclusio

    Epstein-Barr and BK virus in cancerous and noncancerous prostate tissue

    Somayeh Shatizadeh Malekshahi, Jila Yavarian, Robabeh Salehi, Farhad Babaei, Seyed Ali Ahmadi, Nastaran Ghavami, Maryam Naseri, Mostafa Hosseini, Talat Mokhtari-Azad, Nazanin-Zahra Shafiei-Jandaghi
    Journal PapersFuture Virology , Volume 15 , Issue 1, 2020 January , {Pages 13-17 }

    Abstract

    Aim: We conducted a case–control study to examine the presence of BK virus (BKV) and Epstein barr virus (EBV) genome in prostate specimens of benign prostatic hyperplasia (BPH) and prostate cancer (PCa) in Iran. Materials & methods: 64 paraffin-embedded PCa specimens were included as case subjects and 57 paraffin-embedded BPH specimens as control. DNA extraction was carried out by phenol–chloroform technique and PCR for detection of BKV and EBV. Results: 90 (73%) out of 121 specimens were collected by prostatectomy and 31 (27%) by transurethral resection of the prostate. BKV was not detected in any of the samples and one positive EBV was reported. Conclusion: These findings provide further evidence against a causative role of BKV and EB

    First Cases of SARS-CoV-2 in Iran, 2020: Case Series Report

    Jila Yavarian, Nazanin-Zahra Shafiei-Jandaghi, Kaveh Sadeghi, Somayeh Shatizadeh Malekshahi, Vahid Salimi, Ahmad Nejati, Fatemeh Ajaminejad, Nastaran Ghavvami, Fatemeh Saadatmand, Saeedeh Mahfouzi, Ghazal Fateminasab, Najmeh Parhizgari, Kobra RAZAVI, Soad
    Journal PapersIranian Journal of Public Health , 2020 August 9, {Pages }

    Abstract

    In Jan 2020, the outbreak of the 2019 novel coronavirus (SARS-CoV-2) in Wuhan, Hubei Province of China spread increasingly to other countries worldwide which WHO declared it as a public health emergency of international concern. Iran was included in the affected countries. Throat swab specimens were collected and tested by using real-time reverse transcription PCR (RT-PCR) kit targeting the E region for screening and RNA dependent RNA polymerase for confirmation. Conventional RT-PCR was conducted for the N region and the PCR products were sequenced by Sanger sequencing. The first seven cases of SARS-CoV-2 infections were identified in Qom, Iran. This report describes the clinical and epidemiological features of the first cases of SARS-CoV-2

    Phylogenetic analysis and circulation pattern of human metapneumovirus strains in children with acute respiratory infection in Iran, 2014–2015

    Abouzar Babaei, Somayeh Shatizadeh Malekshahi, Neda Pirbonyeh, Jamal Sarvari, Afagh Moattari
    Journal PapersFuture Virology , Volume 15 , Issue 7, 2020 July , {Pages 419-427 }

    Abstract

    Aim: The aim of the present study was to investigate the prevalence and genetic variation of the human metapneumovirus (HMPV) G gene in children less than 8 years old with acute respiratory tract infections in Iran during 2014–2015. Materials & methods: To this end, 110 nasal swabs were tested for HMPV F gene. All positive samples were tested for the full length of HMPV G gene, then sequenced and analyzed for phylogenetic grouping. Results: Six (5.45%) out of 110 samples were positive for HMPV gene. Our HMPV sequences clustered into two main clusters: A2b (five isolates) and B1 (one isolate). The dN/dS ratio showed the presence of negative selective pressure. Conclusion: A2b was the predominant genotype during the study period in southwes

    Detection of human herpes viruses 1-5 in miscarriage: A case-control study

    Javad Charostad, Talat Mokhtari-Azad, Jila Yavarian, Nastaran Ghavami, Seyed Mahmood Seyed Khorrami, Emad Behboudi, Somayeh Jalilvand, Somayeh Shatizadeh Malekshahi, Nazanin Zahra Shafiei-Jandaghi
    Journal PapersInternational Journal of Reproductive BioMedicine , Volume 18 , Issue 7, 2020 July , {Pages 501 }

    Abstract

    BackgroundMiscarriage is the spontaneous pregnancy loss before 24 wk of gestation. The incidence rate of miscarriage over the past few decades has shown steady or even growing trends. Viral intrauterine infections are one of the probable etiological causes of miscarriage. Previous evidence have shown that human herpes viruses (HHVs) could be considered as the potential reasons for intrauterine infections and adverse pregnancy outcomes.ObjectiveThis case-control study aimed to detect HHV1-5 DNAs in placental tissues and assess their association with miscarriage during the first 24 wk of pregnancy in spontaneous and therapeutic abortions.Materials and MethodsPlacental tissues from 83 women with spontaneous abortions during the first and the s

    The landscape of extrapulmonary manifestations of human parainfluenza viruses: A systematic narrative review

    Mohammad Farahmand, Somayeh Shatizadeh Malekshahi, Mohammad Reza Jabbari, Mohammad Shayestehpour
    Journal Papers , 2020 December 3, {Pages }

    Abstract

    Human parainfluenza virus (HPIV) infection is associated with every kind of respiratory tract illnesses, including the common cold, laryngotracheobronchitis (i.e., croup), tracheobronchitis, bronchiolitis, and pneumonia, in both children and adults. Although HPIVs are common respiratory pathogens, there are increasing reports about extrapulmonary manifestations of HPIVs infection. Each of the HPIVs could produce infection of other organs (CNS, heart, myocardium, etc.) in all age groups who are either immunocompetent or immunocompromised. This review aimed at summarizing the available data on clinical manifestations of HPIV infection outside the respiratory tract from 1961 to 2020. The findings support the possibility of extrapulmonary infe

    Genetic characterization of G protein in respiratory syncytial virus ON-1 genotype in Tehran

    Somayeh Shatizadeh Malekshahi, Yazdan Samieipour, Ali Akbar Rahbarimanesh, Anahita Izadi, Nastaran Ghavami, Shaghayegh Razaghipour, Maryam Naseri, Talat Mokhtari-Azad, Vahid Salimi
    Journal PapersFuture Virology , Issue 0, 2020 October , {Pages }

    Abstract

    Aim: We investigated the genetic characterization of the respiratory syncytial virus (RSV) ON-1 genotypes and their different lineages based on the G gene among children< 2 years of age presenting with acute respiratory tract infections in Tehran, Iran. Materials & methods: A phylogenetic tree from the Iranian samples and ON-1 strains of various parts of the world were constructed. The amino acid composition of the RSV G protein of the ON-1 genotype was mapped. Results: Human RSV ON-1 genotypes from the Iranian samples clustered in three lineages. The most common amino acid substitutions were as follows: X218Q, I240S, L289P, Y304H and L310P. Conclusion: Continuing molecular epidemiological surveys in other regions of Iran will provide deepe

    Usage of peptidases by SARS‐CoV‐2 and several human coronaviruses as receptors: A mysterious story

    Somayeh Shatizadeh Malekshahi, Jila Yavarian, Nazanin‐Zahra Shafiei‐Jandaghi
    Journal Papers , 2020 December 21, {Pages }

    Abstract

    Coronaviruses recognize a variety of host receptors to infect many humans and animals. Newly emerged severe acute respiratory syndrome coronavirus2 (SARS‐CoV‐2), recognizes angiotensin‐converting enzyme 2 (ACE2) to gain entry into different cells. Interestingly, besides SARS‐CoV2, four other human coronaviruses (HCoVs) use three different ectopeptidases (ACE2, dipeptidyl peptidase 4 and aminopeptidase N) as receptors independent of their common peptidase activity. This issue has led to the important question “why do several HCoVs rely on peptidases as their receptors?”. In this article we discussed to answer this question. Mostly, it seems that the use of peptidases by HCoVs may be more related to their widespread presence on t

    Survey of BK Virus in Renal Transplant Recipients in Iran: A Systematic Review and Meta-Analysis

    Somayeh Shatizadeh Malekshahi, Hoorieh Soleimanjahi, Fariba Dorostkar, Vahid Salimi, Mohammad Farahmand
    Journal Papers , 2020 December 17, {Pages 09-Jan }

    Abstract

    Introduction: BK virus (BKV) infection in renal transplant (RT) recipients can cause hemorrhagic cystitis, transient renal dysfunction, and BKV nephropathy (BKVN). The prevalence and significance of BKV in RT recipients remain to be clarified in the Iranian population. The purpose of this review is to summarize the overall prevalence of BKV infection in RT recipients from previously published studies in Iran. Methods: We systematically reviewed articles through a comprehensive search of the main electronic and Persian national databases up to November 2019. Results: The overall pooled prevalence of BKV infection among the Iranian population was 23%(95% CI; 15–33%). Comparing these studies revealed that the prevalence of BKV in plasma samp

    The landscape of extrapulmonary manifestations of human parainfluenza viruses: A systematic narrative

    Mohammad Farahmand, Somayeh Shatizadeh Malekshahi, Mohammad Reza Jabbari, Mohammad Shayestehpour
    Journal Papers , 2020 January , {Pages }

    Abstract

    Human parainfluenza virus (HPIV) infection is associated with every kind of respiratory tract illnesses, including the common cold, laryngotracheobronchitis (ie croup), tracheobronchitis, bronchiolitis, and pneumonia, in both children and adults. Although HPIVs are common respiratory pathogens, there are increasing reports about extrapulmonary manifestations of HPIVs infection. Each of the HPIVs could produce infection of other organs (central nervous system, heart, myocardium, etc.) in all age groups who are either immunocompetent or immunocompromised. This review aimed at summarizing the available data on clinical manifestations of HPIV infection outside the respiratory tract from 1961 to 2020. The findings support the possibility of extr

    Extra Pulmonary Manifestations of COVID-19: A Narrative Review

    Ameneh Omidi, Somayeh Shatizadeh Malekshahi, Parsa Veisi
    Journal Papers , Volume 23 , 2020 September 10, {Pages 0-0 }

    Abstract

    Coronaviruses are a large family of viruses that usually cause mild to moderate upper respiratory tract illnesses. The newly emerged sever acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported in late 2019 and causes coronavirus disease 2019 (COVID-19). Due to the novelty of the virus, new scientific evidence on various aspects of COVID-19 is reported in the literature continuously. Common symptoms of COVID-19 include fever, dry cough, fatigue, myalgia, arthralgia and Shortness of breath. Some articles have also reported on various manifestations of SARS-CoV-2 infection outside the respiratory tract. The affected organs are gastrointestinal tract, central nervous system, skin, olfactory system, cardiovascular system, liver, kid

    Introduction of Chromosomally integrated human herpesvirus 6 and its clinical implications

    Somayeh Shatizadeh Malekshahi, Kiana Ketabi
    Journal PapersPathobiology Research , Volume 23 , Issue 4, 2020 June 10, {Pages 55-66 }

    Abstract

    Aims: Human herpes virus 6 (HHV-6) is a ubiquitous virus with a high rate of prevalence worldwide. In recent years, a new form of the virus genome has been identified called Chromosomally integrated HHV-6 (ciHHV-6). Further studies are required to elucidate the relation between ciHHV-6 and other clinical complications. The purpose of this study was to summarize the literature on different clinical aspects of the ciHHV-6 integration and its prevalevce in different communities.Materials and methods: Search keywords include HHV-6, integrated genome, telomeric regions and integrated HHV-6. Scientific databases such as scopus, PubMed and google scholar with no specified start date were used for information collection.Findings: About 1% of global

    Vertical transmission of BK virus in pregnancy: A narrative review

    Mona Shokoofeh, Somayeh Shatizadeh Malekshahi, Haleh Soltanghoraee, Azadeh Soltani
    Journal Papers , Volume 22 , Issue 3, 2020 January , {Pages }

    Abstract

    Background: Primary infection with the BK virus occurs in the tonsils and is transmitted to other tissues and organs, especially the kidneys, by infecting monocytes. Infection with this virus is rarely associated with clinical disease but reactivating the virus in people who have a suppressed immune system can cause kidney or bladder damage. Due to the importance of activating the BK virus in status of immunodeficiency and providing such conditions during pregnancy, the purpose of this study was to summarize the literature on the role of BK virus and its transmission in congenital infection. The results of serological, molecular and studies that have simultaneously performed serological and molecular studies in the field of vertical transmi

    Extrapulmonary Manifestations of Coronavirus Disease 2019: A Narrative Review

    A Omidi, S Shatizadeh Malekshahi, P Veisi
    Journal Papers , , {Pages }

    Abstract

    شناسایی هرپس ویروس های 5-1 در نمونه های سقط جنین: مطالعه مورد شاهدی‎

    J Charostad, T Mokhtari-Azad, J Yavarian, N Ghavami, ...
    Journal Papers , , {Pages }

    Abstract

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    دروس نیمسال جاری

    • دكتري
      ويروس شناسي عمومي نوين ( واحد)
      دانشکده علوم پزشکی، گروه ويروس شناسي
    • دكتري
      زيست شناسي سلولي ومولكولي ( واحد)
    • كارشناسي ارشد
      ويروس شناسي سيستماتيك 1 ( واحد)

    دروس نیمسال قبل

    • كارشناسي ارشد
      ويروس شناسي پزشكي ( واحد)
      دانشکده علوم پزشکی، گروه باكتري شناسي
    • كارشناسي ارشد
      ويروس شناسي پزشكي ( واحد)
    • كارشناسي ارشد
      آربو ويروس شناسي ( واحد)
    • كارشناسي ارشد
      زيست شناسي سلولي مولكولي ( واحد)
    • كارشناسي ارشد
      ايمونولوژي 2 ( واحد)
    • كارشناسي ارشد
      ايمونولوژي 2 ( واحد)
    • 1401
      اسلامي كجيدي, مرضيه
      بررسي شيوع همزمان عفونت فعال ويروس هاي BK، اپشتين بار و سيتومگال و ارتباط با فاكتورهاي ميزباني در بيماران دريافت كننده پيوند كليه
    • 1401
      محمودي, محمد جواد
    • 1399
      غلامي برزكي, مهدي
      ارزيابي رونوشت هاي ژن 1-Syncytin رتروويروس اندوژن W و 2-Syncytin رتروويروس اندوژن FRD و يپش بييني و سنجش microRNAهاي موثر بر رونوشت هاي اين دو ژن در نمونه ها ي سقط مكرر خود به خودي و اندومتريوز در مقايسه با گروه كنترل
      داده ای یافت نشد
      داده ای یافت نشد

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